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Vaccines during pregnancy protect mother and baby from infectious diseases

A selective literature survey by Röbl-Mathieu et al. discusses how vaccines can prevent infectious diseases in pregnant women as well as in unborn and newborn babies. The authors conclude that vaccines are a central element in ante- and postnatal care since they protect the pregnant woman as well as her baby both before and after birth from infectious diseases. To illustrate their argument, Röbl-Mathieu et al. refer to the current vaccination guidelines for tetanus, influenza, pertussis, and hepatitis B for…
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Paediatric clinical trials: industry and non-industry bringing different strengths together

Clinical trials are an essential part of advancing knowledge and improving healthcare worldwide. Advances in paediatric research across the globe to improve the lives of babies, children and young people have dramatically reduced rates in morbidity and mortality and increased the quality of life, for example, reducing sudden infant death, increasing the life expectancy for children with thalassemia, cystic fibrosis etc. Clinical trials within the paediatric population can be conducted as…
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Pre-pregnancy overweight as a risk factor for postpartum depression

Postpartum depression (PPD) affects 10 to 15% of women after giving birth worldwide. PPD is a depressive disorder characterised by fear of failure, emotional ambivalence, and major depressive symptoms which can ultimately impact maternal caregiving and lead to a disturbed mother-to-infant relationship. This in turn can influence the newborn’s long-term development. Thus, identification of underlying risk factors is important. The aetiology of PPD is still not completely understood. Therefore, several studies endeavoured to shed…
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Visual function in preterm infants: Can early interventions help to improve visual function?

The environment and the procedures at the Neonatal Intensive Care Unit (NICU) can be stressful for preterm infants. Thus, brain development might be decelerated, increasing the possibility for visual impairments. However, the clinical trial by Italian researchers has shown that early interventions by parents can have a positive effect on visual functions. Previous research suggests that multisensory stimulation, especially infant massages, can help with brain development and visual maturation in preterm infants. The randomized…
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Disparities in the follow-up of very preterm born children in Europe

With a letter issued in February 2021, a group of researchers presented an analysis of the cross-European disparities of routine follow-up services of children who were born very preterm (<32 weeks of gestational age (GA)). It was found that the mother’s sociodemographic characteristics and her perinatal situation were among the main factors regarding these disparities. Aiming to describe the use of follow-up services in Europe, the research team collected data from obstetric and neonatal records…
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Improving thermoregulation in transported preterm infants

Infants born preterm (<37 weeks of gestation) or with a low birthweight (<2.5 kg) are at high risk for decreasing body temperature during transportation to the hospital. Hypothermia in preterm infants is a risk factor for increased mortality and morbidity (e.g. respiratory distress syndrome). Therefore, effective thermoregulation during transport is of outmost importance. In the study by Glenn et al., interventions were developed to increase the efficacy of thermoregulation in transported…
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What matters to women in the postnatal period?

The postnatal period is an important adjustment period for women, which lasts from after delivery until up to six weeks after birth. During this phase women receive immediate clinical care and community support to ensure the health of mother and child by providing support for breastfeeding practices, monitoring the infants’ development and counselling. Yet, maternity care is often insufficient and differs across countries. To ensure that women receive the best care, a study identified…
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Both preterm and post-term birth increases risk of Autism Spectrum Disorder

The causes of autism spectrum disorder (ASD) are complex and remain unclear. A recent study, involving more than 3.5 million children, now shows that the risk of ASD may slightly increase for each week a baby is born before or after 40 weeks of gestation. Autism spectrum disorder (ASD) is a neurodevelopmental disorder, affecting 1% to 2% of children worldwide. Children with this disease cannot initialize or take part in social communication and have repetitive behaviours. The reasons may be…
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RECAPpreterm Cohort Platform will soon be accessible

RECAPpreterm is a research project developing a unique data platform that will allow researchers to find and use data from very preterm and very low birth weight cohorts to answer research questions.  The Cohort Platform will bring together extensive data from 20 population-based cohorts of children and young adults born very preterm from 13 European countries as well as further cohorts from around the world. End of January, the project’s General…
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Generational effects of COVID-19: Elevated anxiety during pregnancy has negative impact on infants

A self-report questionnaire in pregnant women in Alberta reveals that stress resulting from specific concerns about COVID-19 exceeds expected levels and is higher than that experienced by other groups of people. Social support and physical activity appeared as potential protective factors. The global COVID-19 pandemic has provided a platform to study the impact of severe disease outbreak and subsequent quarantine on mental health issues. Since these issues are heightened in…
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